CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3225
Family Name Aromatase Inhibitor 2-(1h-imidazol-1-yl)-1-(4-nitrophenyl)ethanone Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00286611 Functional Category Investigative Drug with Natural Product
Superfamily Aromatase Inhibitor 2-(1h-imidazol-1-yl)-1-(4-nitrophenyl)ethanone Superfamily
Class Class 715

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Prothrombin Inhibitor Dabigatran Family 7 182
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 6-im... 2 30
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(4-nitrob... 3 5
Aromatase Inhibitor 4-imidazol-1-ylmethylthioxanthen-9-one Family 2 4
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Aromatase and Beta-lactamase inhibitor N-(3-Imidazol-1-yl-prop... 1 1
Cellular tumor antigen p53 and E3 ubiquitin-protein ligase Mdm... 3 2


External ID

Functional Category

Molecule Name

CFAMM00286611 DNC010995 Investigative Drug 2-(1H-Imidazol-1-yl)-1-(4-nitrophenyl)ethanone
CFAMM00286610 DNC010996 Investigative Drug 1-(4-Aminophenyl)-2-(1H-imidazol-1-yl)ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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