CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3227
Family Name Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-carbazole-3-carboxylate Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00286648 Functional Category Investigative Drug with Natural Product
Superfamily Tubulin beta chain and Kinesin-like protein KIF11 Binder Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Sodium channel Ligand GSK1014802 Family 4 92
Dipeptidyl peptidase 4 Inhibitor TAK-100 Family 5 7
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Tubulin beta chain Inhibitor Isopropyl 3-(phenylthio)-1h-indol... 1 7
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 3 4
NS5B protein inhibitor AC1NQMYG family 6 12
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor AG... 1 0
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
NS5B protein inhibitor AC1NQMYP family 5 0
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Collagenase 3 and Matrix metalloproteinase-14 inhibitor 4-[[[5... 2 4
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1
Gonadotropin-releasing hormone receptor ligand methyl 4-[2-[[(... 2 1
Gonadotropin-releasing hormone receptor ligand 4-[2-[[(2S)-2-[... 1 0
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 1 2
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C19 ... 1 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Glycogen synthase kinase 3 beta and Dual specificity tyrosine-... 1 6
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 48
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
Putative NP ZINC15919780 Family 2 0
methyl 4-[(5Z)-5-(1H-indol-3-ylmethylidene)-4-oxo-2-sulfanylid... 1 0
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0
8-carbamoyl-6,7,8,9-tetrahydro-5H-carbazole-1-carboxylate NP Z... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00286648 DNC011002 Investigative Drug methyl 7-tert-butyl-9H-carbazole-3-carboxylate
CFAMM00286640 DNC011012 Investigative Drug 7-tert-butyl-9H-carbazole-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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