CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3234
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand 1,6-bis(4-(3-chlorophenyl)piperazin-1-yl)hexane Family
No. of Seeds 3 No. of Other Members 34
Family Centroid CFAMM00286849 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Binder Superfamily 2
Class Class 2707

Cousin Family NamesSeedsMembers
Dopamine receptor Ligand Domperidone Family 2 21
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
Serotonin re-uptake inhibitor Dibenzazepine Clomipramine Family 2 23
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family 1 21
Gamma-aminobutyric acid A receptor Ligand ELB-139 Family 1 3
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 2
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Kappa-type opioid receptor ligand AGN-PC-077Q4Y family 5 9
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
5-hydroxytryptamine receptor 2C ligand SureCN5872545 family 3 0
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 14 0
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 2 1
5-hydroxytryptamine receptor 4 ligand AC1L4N66 family 2 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 1
Sigma non-opioid intracellular receptor 1 and Sodium-dependent... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00286842 CHEMBL27378 Bioactive SureCN13875118
CFAMM00286846 CHEMBL279906 Bioactive 1-(3-Chlorophenyl)-4-hexylpiperazine
CFAMM00286849 DNC011041 Investigative Drug 1,6-bis(4-(3-chlorophenyl)piperazin-1-yl)hexane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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