CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3258
Family Name Amine oxidase [flavin-containing] B Inhibitor 8-bromo-6-methyl-3-(4'-methoxyphenyl)coumarin Family
No. of Seeds 5 No. of Other Members 44
Family Centroid CFAMM00287194 Functional Category Investigative Drug with Natural Product
Superfamily Amine oxidase [flavin-containing] B Binder Superfamily
Class Class 2225

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Ipriflavone family 62 2480
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Thyroid hormone receptor beta Ligand (3,5-dibromo-4-pentyloxy-... 5 21
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Prostaglandin D2 receptor 2 Ligand 2-(2-benzoyl-4-bromophenoxy... 4 35
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-b... 6 21
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 7
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 2
Free fatty acid receptor 1 ligand AGN-PC-0A9RM3 family 1 0
Squalene--hopene cyclase and Lanosterol synthase inhibitor R17... 1 22
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 6
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
6-bromo-2-oxo-4-phenyl-3,4-dihydrochromene-3-carboxylate NP ZI... 4 0
[4-(6-bromo-2-oxochromen-3-yl)-2-oxochromen-7-yl]oxyacetate NP... 7 0
NP 3-(6-bromo-4h-benzo[d][1,3]dioxin-8-yl)-4h-chromen-4-one Fa... 2 0
[3-(4-bromophenyl)-4-methyl-2-oxochromen-6-yl]oxyacetate NP ZI... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00287181 CHEMBL1835232 Bioactive 3-(4-bromo-3-methoxyphenyl)-6-methylchromen-2-one
CFAMM00287180 CHEMBL1835231 Bioactive 3-(3-bromo-4-methoxyphenyl)-6-methylchromen-2-one
CFAMM00287194 DNC011167 Investigative Drug 8-Bromo-6-methyl-3-(4'-methoxyphenyl)coumarin
CFAMM00287193 DNC011165 Investigative Drug 3-(2-Bromophenyl)-6-methylcoumarin
CFAMM00287172 DNC011166 Investigative Drug 8-Bromo-6-methyl-3-phenylcoumarin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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