CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3273
Family Name Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662 Family
No. of Seeds 31 No. of Other Members 23
Family Centroid CFAMM00287613 Functional Category Investigative Drug with Natural Product
Superfamily Oxytocin receptor and Vasopressin V1a receptor Binder Superfamily
Class Class 2053

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Renin Inhibitor CP-305202 Family 9 30
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Vasopressin V1a receptor and Oxytocin receptor ligand 1-[1-[2-... 3 0
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Acetylcholinesterase and Cholinesterase inhibitor 5-methoxy-7-... 1 18
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 1 7
Aromatase inhibitor isoflavone deriv. 5m family 1 0
DNA-dependent protein kinase catalytic subunit inhibitor 2-mor... 1 4
Hepatocyte growth factor receptor ligand 2-[(2-fluorophenyl)me... 6 11
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 0
NP (e)-6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenzofura... 4 1
NP Agn-pc-01km7v Family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00287643 CHEMBL302297 Bioactive 1-[1-[4-[1-[(2,4-dimethyl-1-oxidopyridin-1-ium-3-yl)methyl]piperidin-4-yl]oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287599 CHEMBL104237 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[(1R)-1-pyridin-4-ylethoxy]benzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287623 CHEMBL71540 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-[[1-oxido-4-(trifluoromethyl)pyridin-1-ium-3-yl]methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287636 CHEMBL69202 Bioactive 1-[1-[2-methoxy-4-[1-[(1-oxido-2-propylpyridin-1-ium-3-yl)methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287609 CHEMBL308460 Bioactive 1-[1-[4-[1-(6,7-dihydro-5H-cyclopenta[b]pyridin-5-yl)piperidin-4-yl]oxy-5-fluoro-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287622 CHEMBL69265 Bioactive 1-[1-[2-methoxy-4-[1-[[1-oxido-4-(trifluoromethyl)pyridin-1-ium-3-yl]methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287597 CHEMBL68816 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-(1-oxido-6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-5-yl)piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287635 CHEMBL265070 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-[(5R)-1-oxido-5,6,7,8-tetrahydroquinolin-1-ium-5-yl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287604 CHEMBL68199 Bioactive 1-[1-[4-[1-[(4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)methyl]piperidin-4-yl]oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287641 CHEMBL105514 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[(1R)-1-(1-oxidopyridin-1-ium-4-yl)ethoxy]benzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287608 CHEMBL322187 Bioactive 1-[1-[2-methoxy-4-[(1R)-1-pyridin-4-ylethoxy]benzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287621 CHEMBL65950 Bioactive 1-[1-[2-methoxy-4-[1-(2-methyl-1-oxidopyridin-1-ium-3-carbonyl)piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287634 CHEMBL66992 Bioactive AGN-PC-072QGB
CFAMM00287627 CHEMBL68480 Bioactive SureCN7358434
CFAMM00287640 CHEMBL302128 Bioactive 1-[1-[5-fluoro-2-methoxy-4-(1-quinolin-5-ylpiperidin-4-yl)oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287607 CHEMBL302029 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-(5,6,7,8-tetrahydroquinolin-5-yl)piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287595 CHEMBL66240 Bioactive 1-[1-[4-[1-[(2-ethyl-1-oxidopyridin-1-ium-3-yl)methyl]piperidin-4-yl]oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287639 CHEMBL303700 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-[[1-oxido-2-(trifluoromethyl)pyridin-1-ium-3-yl]methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287619 CHEMBL308673 Bioactive SureCN7357147
CFAMM00287612 CHEMBL303487 Bioactive 1-[1-[2-methoxy-4-[1-[(4-methyl-1-oxidopyridin-1-ium-3-yl)methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287605 CHEMBL68800 Bioactive 1-[1-[5-fluoro-2-methoxy-4-[1-[(5S)-1-oxido-5,6,7,8-tetrahydroquinolin-1-ium-5-yl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287644 CHEMBL66985 Bioactive SureCN7357293
CFAMM00287600 CHEMBL306416 Bioactive SureCN7388996
CFAMM00287624 CHEMBL66931 Bioactive 1-[1-[2-methoxy-4-[1-[[1-oxido-2-(trifluoromethyl)pyridin-1-ium-3-yl]methyl]piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287637 CHEMBL69201 Bioactive 1-[1-[2-methoxy-4-[1-(1-oxido-5,6,7,8-tetrahydroquinolin-1-ium-5-yl)piperidin-4-yl]oxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
CFAMM00287613 DNC011197 Investigative Drug L-372662

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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