CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3275
Family Name Amine oxidase [flavin-containing] B Inhibitor 2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole Family
No. of Seeds 6 No. of Other Members 44
Family Centroid CFAMM00287679 Functional Category Investigative Drug
Superfamily Amine oxidase [flavin-containing] B Inhibitor 2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole Superfamily
Class Class 2719

Cousin Family NamesSeedsMembers
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Metabotropic glutamate receptor 5 Ligand 4-(2-(3-fluorophenyl)... 8 1
Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethyny... 2 10
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Reverse transcriptase Inhibitor PT-316 Family 8 2
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 8
Amine oxidase [flavin-containing] B inhibitor 4-(4-fluoropheny... 3 4
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Fructose-1,6-bisphosphatase 1 inhibitor AGN-PC-079IZF family 1 3


External ID

Functional Category

Molecule Name

CFAMM00287647 CHEMBL1253845 Bioactive AGN-PC-09M7EL
CFAMM00287686 CHEMBL1253699 Bioactive AGN-PC-08VISG
CFAMM00287678 DNC011206 Investigative Drug 2-(2-cyclohexylidenehydrazinyl)-4-p-tolylthiazole
CFAMM00287675 DNC011208 Investigative Drug 2-(2-cyclopentylidenehydrazinyl)-4-phenylthiazole
CFAMM00287665 DNC011205 Investigative Drug 2-(2-cycloheptylidenehydrazinyl)-4-phenylthiazole
CFAMM00287679 DNC011207 Investigative Drug 2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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