CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Thyroid hormone receptor beta Ligand GC-1 Family
No. of Seeds 2 No. of Other Members 62
Family Centroid CFAMM00187691 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Hepatocyte growth factor and Fibroblast growth factor 1 Binder Superfamily
Class Class 1536

Cousin Family NamesSeedsMembers
Bis(5'-adenosyl)-triphosphatase Inhibitor Fructose Family 3 45
Fibroblast growth factor 1 and Hepatocyte growth factor Inhibi... 2 2
6-phosphogluconate dehydrogenase, decarboxylating Inhibitor 6-... 2 11
Hydroxy Acids and Derivatives Metabolite 2-Hydroxyadipic acid ... 4 2
Lactones Metabolite Erythrono-1,4-lactone Family 3 5
Monosaccharides Metabolite 3-Deoxy-D-glycero-D-galacto-2-nonul... 2 8
Alkyl Glycosides Metabolite Valproic acid glucuronide Family 2 14
Tetrasaccharides Metabolite Maltulose Family 3 5
Trisaccharides Metabolite 2-Fucosyllactose Family 9 1
Lactones Metabolite Solerol Family 1 0
Trisaccharides Metabolite 4-O-(4-O-Methyl-alpha-D-glucopyranur... 2 23
Lactones Metabolite (4S,6S)-3,4,5,6-Tetrahydro-4-hydroxy-6-met... 2 1
Lactones Metabolite 2-Deoxy-L-ribono-1,4-lactone Family 1 0
Sugar Acids and Derivatives Metabolite Trichloroethanol glucur... 1 0


External ID

Functional Category

Molecule Name

CFAMM00187691 DNC000680 Investigative Drug GC-1
CFAMM00187682 DNC003282 Investigative Drug Gluconolactone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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