CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3300
Family Name 5-hydroxytryptamine receptor 6 Ligand 4-(piperazin-1-yl)-3-tosyl-1h-indazole Family
No. of Seeds 18 No. of Other Members 75
Family Centroid CFAMM00288581 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand 4-(piperazin-1-yl)-3-tosyl-1h-indazole Superfamily
Class Class 2728

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor 3-[2-(1-benzyl-piperidin-4-yl)-... 2 9
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 12 0
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 4 16
5-hydroxytryptamine receptor 6 ligand SureCN3535300 family 5 3
5-hydroxytryptamine receptor 6 ligand N-[2-(dimethylamino)ethy... 1 0
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 3 1
Tyrosine-protein kinase ITK/TSK inhibitor (3Z)-3-(6-methylindo... 2 40
5-hydroxytryptamine receptor 6 ligand SureCN4201696 family 2 0
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
5-hydroxytryptamine receptor 6 ligand 1-sulfonylindazole, 6d f... 9 2
Aurora kinase B and Aurora kinase A inhibitor SureCN5594082 fa... 2 3
Ketohexokinase inhibitor 3-methylsulfanyl-1-phenyl-6-(1,2,3,6-... 5 6
Focal adhesion kinase 1 inhibitor 8-(4-ethylphenyl)-1,5-dimeth... 1 2
Dual specificity protein kinase TTK and Mitogen-activated prot... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00288561 CHEMBL1278092 Bioactive SureCN3948917
CFAMM00288592 CHEMBL1642880 Bioactive 3-(benzenesulfonyl)-N-piperidin-4-yl-2H-indazol-5-amine;hydrochloride
CFAMM00288619 CHEMBL1277999 Bioactive 3-(3-fluorophenyl)sulfonyl-5-(4-methylpiperazin-1-yl)-2H-indazole
CFAMM00288560 CHEMBL1278090 Bioactive SureCN3949874
CFAMM00288578 CHEMBL1277105 Bioactive SureCN3078215
CFAMM00288591 CHEMBL1642881 Bioactive AGN-PC-09QJD1
CFAMM00288624 CHEMBL1277917 Bioactive SureCN3948910
CFAMM00288589 CHEMBL1642883 Bioactive AGN-PC-09QIIK
CFAMM00288588 CHEMBL1642884 Bioactive AGN-PC-09QK7K
CFAMM00288587 CHEMBL1642886 Bioactive AGN-PC-09QL40
CFAMM00288549 CHEMBL1276925 Bioactive 3-(3-methylphenyl)sulfonyl-5-(4-methylpiperazin-1-yl)-2H-indazole
CFAMM00288593 CHEMBL1642889 Bioactive 3-naphthalen-2-ylsulfonyl-N-piperidin-4-yl-2H-indazol-5-amine;hydrochloride
CFAMM00288620 CHEMBL1277998 Bioactive 3-(2-fluorophenyl)sulfonyl-5-(4-methylpiperazin-1-yl)-2H-indazole
CFAMM00288586 CHEMBL1642887 Bioactive N-piperidin-4-yl-3-[4-(trifluoromethyl)phenyl]sulfonyl-2H-indazol-5-amine;hydrochloride
CFAMM00288555 CHEMBL1277467 Bioactive AGN-PC-088EVX
CFAMM00288553 DNC011280 Investigative Drug 6-(piperazin-1-yl)-3-tosyl-1H-indazole
CFAMM00288581 DNC011278 Investigative Drug 4-(piperazin-1-yl)-3-tosyl-1H-indazole
CFAMM00288580 DNC011279 Investigative Drug 5-(4-Methylpiperazin-1-yl)-3-tosyl-1H-indazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24631 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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