CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3319
Family Name Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor NSC-665126 Family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00288791 Functional Category Investigative Drug
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Ribosyldihydronicotinamide dehydrogenase [quinone] Binder Superfamily
Class Class 2102

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Neuronal acetylcholine receptor subunit alpha-4 Ligand Varenic... 3 54
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Glucagon receptor Ligand Dwlip-gcgrrx Family 5 26
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-(4-phenylb... 6 32
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cathepsin S Inhibitor 6-(3-(trifluoromethyl)phenyl)picolinonit... 7 2
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 3-fluoro-5-(2-methylq... 3 2
Metabotropic glutamate receptor 5 Ligand 3-chloro-5-(2-methylq... 3 4
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Trypsin Inhibitor 4-(5-nitro-indol-1-ylmethyl)-benzamidine Family 2 0
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Corticotropin-releasing factor receptor 1 ligand 3,7-dimethyl-... 3 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9UNU family 3 0
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SQ6 family 3 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Glucocorticoid receptor ligand 1,1,1-trifluoro-2-[(1-methyl-3,... 3 4
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 2
Neuronal acetylcholine receptor subunit alpha-6 ligand AGN-PC-... 2 0
Capsid scaffolding protein inhibitor AC1O583J family 5 1
Thymidylate synthase inhibitor AGN-PC-00EUGY family 2 7
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Lysine-specific demethylase 4E and Lethal(3)malignant brain tu... 1 1
Potassium voltage-gated channel subfamily H member 2 ligand 1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00288791 DNC011325 Investigative Drug NSC-665126

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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