CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3324
Family Name Induced myeloid leukemia cell differentiation protein Mcl-1 and Mannose-6-phosphate isomerase Inhibitor Gnf-pf-5134 Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00288805 Functional Category Investigative Drug
Superfamily Calmodulin Inhibitor Aprindine Superfamily
Class Class 521

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Dopamine receptor Ligand Domperidone Family 2 21
Alpha adrenergic receptor Ligand Droperidol Family 20 244
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Histamine H1 receptor Ligand Epinastine Family 2 26
Motilin receptor Ligand GSK962040 Family 30 457
Nociceptin receptor Ligand J-113397 Family 3 14
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
Cholinesterase Inhibitor (-)-debromoflustramine B Family 2 14
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Reverse transcriptase Inhibitor Tibo Family 2 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Translocator protein inhibitor CHEMBL2332254 family 6 1
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Nociceptin receptor and Mu-type opioid receptor ligand spiropi... 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRYI family 2 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 3 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 1 0
Type-2 angiotensin II receptor ligand SureCN3515537 family 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Mu-type opioid receptor ligand 1-[[(3S)-2-[[(2R)-1-[(4-cyanoph... 1 0
Beta-lactamase and Prelamin-A/C inhibitor CHEMBL1560571 family 1 5
Substance-P receptor ligand (2S)-2-N-[2-[(3,5-dimethylphenyl)m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00288805 DNC011348 Investigative Drug GNF-PF-5134

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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