CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3329
Family Name Voltage-dependent N-type calcium channel subunit alpha-1B Ligand NSC-87509 Family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00288830 Functional Category Investigative Drug with Natural Product
Superfamily Rotenone Superfamily
Class Class 776

Cousin Family NamesSeedsMembers
DNA binder anthracycline analog Doxorubicin family 9 32
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
taste receptor Ligand Cynarin Family 6 124
Agrimophol family 10 22
Chromomycin A3 family 7 14
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Endothelin-1 receptor Ligand PD156707 Family 41 211
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Acetylcholinesterase Inhibitor Territrem B Family 3 21
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
Protein kinase C alpha type Inhibitor Acetoside Family 5 39
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-hydroxygarvin A Family 2 2
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
72 kDa type IV collagenase Inhibitor Lithospermic Acid Family 1 0
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 1 0
Calmodulin inhibitor CHEMBL2408940 family 1 0
Survival motor neuron protein and Prelamin-A/C inhibitor CHEMB... 2 32
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 4 10
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 1 0
72 kDa type IV collagenase inhibitor [(2S,3S,4R)-4-(4,5-dihydr... 1 0
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Prenol Lipids Metabolite 13-Hydroxydihydromelleolide Family 3 0
Prenol Lipids Metabolite Rosmadial Family 1 0
Acenes Metabolite Musanolone D Family 2 1
Acenes Metabolite 1-Hydroxypyrene glucuronide Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00288830 DNC011362 Investigative Drug NSC-87509

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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