CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID333
Family Name Farnesyltransferase beta subunit, putative and Protein farnesyltransferase subunit beta Inhibitor RPR-114334 Family
No. of Seeds 6 No. of Other Members 18
Family Centroid CFAMM00187815 Functional Category Investigative Drug
Superfamily Farnesyltransferase beta subunit, putative and Protein farnesyltransferase subunit beta Inhibitor RPR-114334 Superfamily
Class Class 1299

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Mitogen-activated protein kinase 14 inhibitor ethyl 2-[[3-(2,4... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00187817 CHEMBL48488 Bioactive (2S)-2-[[5-[[(2R)-2-amino-3-sulfanylpropyl]amino]naphthalene-1-carbonyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00187823 CHEMBL54044 Bioactive (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00187836 CHEMBL28325 Bioactive GGTI-286
CFAMM00187831 DNC000688 Investigative Drug GGTI-298
CFAMM00187815 DNC004236 Investigative Drug RPR-114334
CFAMM00187828 DNC004228 Investigative Drug RPR-113829

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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