CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3338
Family Name Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-6-nitro-2-piperazin-1-yl-quinoline Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00288945 Functional Category Investigative Drug
Superfamily Sodium-dependent serotonin transporter and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 1 0
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquina... 2 1
Histamine H4 receptor and Histamine H3 receptor ligand 7-(fura... 2 2
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
5-hydroxytryptamine receptor 3A and Histamine H4 receptor liga... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
Dual specificity protein kinase CLK4 and Dual specificity tyro... 6 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 2
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Cysteine protease and Cathepsin L1 inhibitor AGN-PC-076NDO family 1 0
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00288926 CHEMBL1935574 Bioactive 7-(furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine
CFAMM00288945 DNC011382 Investigative Drug 4-Furan-2-yl-6-nitro-2-piperazin-1-yl-quinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26416 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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