CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3341
Family Name Reverse transcriptase Inhibitor PT-102 Family
No. of Seeds 8 No. of Other Members 12
Family Centroid CFAMM00289038 Functional Category Investigative Drug
Superfamily Reverse transcriptase Inhibitor PT-102 Superfamily
Class Class 2106

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Histamine H1 receptor Ligand Pheniramine Family 10 380
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
Transient receptor potential cation channel subfamily V member... 16 295
Transient receptor potential cation channel subfamily V member... 6 66
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Adenosine receptor A1 and Adenosine receptor A2a Ligand 3-benz... 1 6
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Transient receptor potential cation channel subfamily V member... 2 26
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Macrophage migration inhibitory factor Inhibitor 1-(2-chloroph... 2 22
Cathepsin L1 Inhibitor (3-bromobenzoylpyridine)thiosemicarbazo... 1 0
Reverse transcriptase Inhibitor PT-115 Family 7 19
Reverse transcriptase Inhibitor PT-113 Family 3 4
Reverse transcriptase Inhibitor PT-109 Family 6 7
Metabotropic glutamate receptor 5 Ligand 7-bromo-n-(3-bromophe... 1 1
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Reverse transcriptase/RNaseH inhibitor 181305-50-0 family 1 0
Acetylcholinesterase and Cholinesterase inhibitor 2-amino-6-[3... 1 4
Reverse transcriptase/RNaseH inhibitor PETT deriv. 13 family 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 2
C-C chemokine receptor type 3 ligand CHEMBL360308 family 1 2


External ID

Functional Category

Molecule Name

CFAMM00289039 DNC012883 Investigative Drug TROVIRDINE HYDROCHLORIDE
CFAMM00289020 DNC011399 Investigative Drug HI-241
CFAMM00289038 DNC012302 Investigative Drug PT-102
CFAMM00289037 DNC011387 Investigative Drug HI-172
CFAMM00289032 DNC012303 Investigative Drug PT-104
CFAMM00289015 DNC011428 Investigative Drug TROVIRDINE
CFAMM00289030 DNC011416 Investigative Drug HI-240
CFAMM00289021 DNC011396 Investigative Drug HI-242

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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