CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3345
Family Name Aldose reductase Inhibitor 7-hydroxy-6-nitro-2-phenyl-chromen-4-one Family
No. of Seeds 2 No. of Other Members 17
Family Centroid CFAMM00289123 Functional Category Investigative Drug with Natural Product
Superfamily Aldose reductase Inhibitor 7-hydroxy-6-nitro-2-phenyl-chromen-4-one Superfamily
Class Class 2742

Cousin Family NamesSeedsMembers
Vitamin K epoxide reductase complex subunit 1 Inhibitor Acenoc... 2 46
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 6-nitr... 5 19
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
Cytosolic phospholipase A2 beta inhibitor 4-[3-(4-decoxyphenox... 1 3
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 inhibi... 1 23
Nuclear receptor ROR-gamma and Retinal dehydrogenase 1 ligand ... 1 8
Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 i... 1 1
Estrogen receptor beta and Estrogen receptor ligand 8-amino-3-... 2 2
Putative NP ZINC11868874 Family 13 1
(E)-1-(2,4-dimethoxy-6-methylphenyl)-3-(4-nitrophenyl)prop-2-e... 1 0
Putative NP ZINC02414327 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00289124 CHEMBL268675 Bioactive 6-amino-5,7-dihydroxy-2-phenylchromen-4-one
CFAMM00289123 DNC011408 Investigative Drug 7-Hydroxy-6-nitro-2-phenyl-chromen-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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