CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3347
Family Name Reverse transcriptase Inhibitor PT-115 Family
No. of Seeds 7 No. of Other Members 19
Family Centroid CFAMM00289164 Functional Category Investigative Drug
Superfamily Reverse transcriptase Binder Superfamily 2
Class Class 1708

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mepyramine Family 5 65
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Reverse transcriptase Inhibitor PT-102 Family 8 12
Reverse transcriptase Inhibitor HI-244 Family 1 0
Reverse transcriptase/RNaseH inhibitor 1-[2-(6-chloro-3-ethoxy... 7 5
Reverse transcriptase/RNaseH inhibitor AC1MHDM5 family 2 0
Reverse transcriptase/RNaseH inhibitor 1-(5-chloropyridin-2-yl... 3 0
Reverse transcriptase/RNaseH inhibitor PETT deriv. 14 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00289156 CHEMBL402265 Bioactive 181305-40-8
CFAMM00289147 CHEMBL253369 Bioactive 172505-89-4
CFAMM00289161 CHEMBL253186 Bioactive 181305-42-0
CFAMM00289160 CHEMBL252964 Bioactive 181305-23-7
CFAMM00289167 DNC011415 Investigative Drug HI-236
CFAMM00289174 DNC012529 Investigative Drug PT-112
CFAMM00289164 DNC012513 Investigative Drug PT-115

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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