CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3351
Family Name Arachidonate 5-lipoxygenase Inhibitor 4,5-dimethoxy-10h-anthracen-9-one Family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00289191 Functional Category Investigative Drug
Superfamily Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfarin Superfamily
Class Class 442

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Danthron family 11 141
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Steryl-sulfatase Inhibitor 3-{4-[(aminosulfonyl)oxy]benzoyl}ph... 5 3
Steryl-sulfatase Inhibitor Sulfamic Acid 2-nonyl-4-oxo-4h-chro... 4 68
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-hydroxygarvin A Family 2 2
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Tyrosine-protein phosphatase non-receptor type 1 Ligand Formyl... 1 1
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Amine oxidase [flavin-containing] B inhibitor 5-(4,4,4-trifluo... 2 9
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7
Sterol 26-hydroxylase, mitochondrial and 1,25-dihydroxyvitamin... 1 2
Thioredoxin glutathione reductase and Voltage-dependent N-type... 1 3
Acetylcholinesterase inhibitor 5,7-Dimethoxy-2-methyl-indan-1-... 1 0
Indoleamine 2,3-dioxygenase 1 inhibitor AGN-PC-04S2CP family 1 3
Acenes Metabolite Lacinilene C Family 2 3
Acenes Metabolite Musanolone D Family 2 1
Naphthofurans Metabolite Pyrocurzerenone Family 1 9
Putative NP ZINC31158464 Family 3 5
2,5,8-triacetyloxy-3,4-dioxonaphthalen-1-olate NP Agn-pc-094ek... 1 0
(6-bromo-5,8-dioxonaphthalen-1-yl) acetate NP 6-bromo-5,8-diox... 1 1
NP 4-(5-fluoro-3-methylbenzofuran-2-yl)-7,8-dihydrocyclopenta[... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00289191 DNC011430 Investigative Drug 4,5-Dimethoxy-10H-anthracen-9-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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