CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3375
Family Name Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hydroxy-n-methyl-acetamide Family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00289783 Functional Category Investigative Drug
Superfamily Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hydroxy-n-methyl-acetamide Superfamily
Class Class 2572

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Arachidonate 5-lipoxygenase Inhibitor Bw A4C Family 3 18
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Galectin-3 Inhibitor 2,3,5,6-tetrafluoro-4-methoxy-benzamide F... 1 0
Poly [ADP-ribose] polymerase 1 Inhibitor 3-methoxybenzamide Fa... 2 23
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-ph... 1 3
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Histamine H3 receptor Ligand A-349821 Family 49 228
Interstitial collagenase Inhibitor N-hydroxy-4-(4-methoxy-phen... 6 4
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Neutrophil elastase and Urokinase-type plasminogen activator I... 1 3
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Matrix metalloproteinase-9 and Collagenase 3 Inhibitor 4-amino... 1 8
Histone deacetylase 1 Inhibitor N-hydroxy-8-(2-methoxyphenyl)-... 2 14
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-butoxy... 1 1
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-[... 2 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 14
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 12
Arachidonate 5-lipoxygenase inhibitor methyl 5-[1-(2-butyl-1-b... 2 4
Trace amine-associated receptor 1 ligand SureCN13886619 family 1 1
Histamine H3 receptor ligand (E)-1-[(2S)-2-(pyrrolidin-1-ylmet... 1 1
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2
Transient receptor potential cation channel subfamily V member... 1 0
Lysosomal alpha-glucosidase inhibitor MLS000587024 family 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-02TTXV family 1 0
N-(2-hydroxyethyl)-1-benzoxepine-4-carboxamide NP N-(2-hydroxy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00289786 DNC011611 Investigative Drug 4-Butoxy-N-hydroxy-N-methyl-benzamide
CFAMM00289793 DNC011676 Investigative Drug 3-(4-Butoxy-phenyl)-N-hydroxy-N-methyl-acrylamide
CFAMM00289783 DNC011652 Investigative Drug 2-(4-Butoxy-phenyl)-N-hydroxy-N-methyl-acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23964 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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