CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3378
Family Name Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4]thiazepin-11-one Family
No. of Seeds 1 No. of Other Members 14
Family Centroid CFAMM00289859 Functional Category Investigative Drug
Superfamily Cholinesterase and Reverse transcriptase Binder Superfamily
Class Class 545

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Propiomazine Family 4 10
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Integrin beta-3 Inhibitor L-750034 Family 7 38
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Thyroid hormone receptor beta ligand CHEMBL1593113 family 1 4
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
C-C chemokine receptor type 2 ligand AGN-PC-03L0X5 family 13 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 4 0
Angiotensin-converting enzyme inhibitor 6-methyl-4-(4-methylph... 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Sodium-dependent serotonin transporter inhibitor AGN-PC-077M6B... 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-077M6A... 1 1
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-0760MQ f... 1 2
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 2


External ID

Functional Category

Molecule Name

CFAMM00289859 DNC011617 Investigative Drug 10-Propyl-10H-dibenzo[b,f][1,4]thiazepin-11-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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