CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID338
Family Name Apoptosis regulator Bcl-2 Inhibitor Gossypol Family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00188035 Functional Category Investigative Drug with Human Metabolite
Superfamily Apoptosis regulator Bcl-2 Inhibitor Gossypol Superfamily
Class Class 1541

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Rotenone family 16 107
Danthron family 11 141
Substance-P receptor Ligand CI-1021 Family 1 0
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
DNA topoisomerase 2-beta Inhibitor Demethylzeylasterone Family 1 2
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-benzyl-3,17-... 1 1
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 6 13
Aldehyde dehydrogenase, cytosolic 1 and Aldehyde dehydrogenase... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00188035 DNC000701 Investigative Drug Gossypol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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