CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3381
Family Name Arachidonate 5-lipoxygenase Inhibitor Phenanthrene-3-carboxylic Acid Hydroxyamide Family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00289947 Functional Category Investigative Drug
Superfamily Arachidonate 5-lipoxygenase and MO15-related protein kinase Pfmrk Binder Superfamily
Class Class 2704

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Aldose reductase Inhibitor Alrestatin Family 2 11
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-4-isobutyl-ben... 4 43
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Poly [ADP-ribose] polymerase 1 Inhibitor 3,4-dihydro-5-methyl-... 3 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Liver carboxylesterase 1 Inhibitor Acenanthrene-9,10-dione Family 2 12
Serine/threonine-protein kinase Chk1 Inhibitor 6-(3-aminopropy... 2 7
Poly [ADP-ribose] polymerase 1 Inhibitor 5-aminoisoquinolin-1(... 2 8
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Histone deacetylase 1 Inhibitor N-hydroxy-6-oxo-6-phenylhexana... 7 7
Histone deacetylase 1 Inhibitor N-hydroxy-7-(naphthalen-2-yl)-... 3 2
Histone deacetylase 1 Inhibitor N-hydroxy-8-(naphthalen-2-yl)n... 6 3
MO15-related protein kinase Pfmrk Inhibitor N'-(2-fluorobenzoy... 1 2
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-3-phe... 7 7
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2-nap... 3 3
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2,3,3... 1 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
Amine oxidase [flavin-containing] A inhibitor 9,10-dichloro-N-... 1 0
Protease inhibitor SureCN6172401 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00289945 DNC011660 Investigative Drug Naphthalene-2-carboxylic acid hydroxyamide
CFAMM00289950 DNC013435 Investigative Drug N-hydroxy-1-naphthamide
CFAMM00289948 DNC011685 Investigative Drug N-Hydroxy-4-naphthalen-2-yl-benzamide
CFAMM00289947 DNC011629 Investigative Drug Phenanthrene-3-carboxylic acid hydroxyamide
CFAMM00289953 DNC011656 Investigative Drug N-Hydroxy-4-naphthalen-1-yl-benzamide
CFAMM00289946 DNC011707 Investigative Drug Anthracene-2-carboxylic acid hydroxyamide
CFAMM00289952 DNC011651 Investigative Drug Phenanthrene-2-carboxylic acid hydroxyamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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