CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3398
Family Name Histamine H3 receptor Ligand GT-2016 Family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00290450 Functional Category Investigative Drug
Superfamily thyrotropin-releasing hormone analog Taltirelin Superfamily
Class Class 735

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
thyrotropin-releasing hormone analog Taltirelin Family 7 29
Polaprezinc family 2 19
Histamine H3 receptor Ligand Cipralisant Family 36 70
Cadherin-2 Inhibitor Exherin Family 2 9
Histamine H3 receptor and Histamine H4 receptor Ligand Thioper... 8 12
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(... 26 80
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Histamine H2 receptor and Histamine H3 receptor ligand N,N'-bi... 2 1
Histamine H3 receptor ligand SureCN7961197 family 1 0
Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(2,4-difluor... 5 0
Histamine H4 receptor and Histamine H3 receptor ligand AGN-PC-... 1 2
Glucocorticoid receptor ligand SureCN13513652 family 1 0
Histamine H2 receptor and Histamine H1 receptor ligand N-[N'-[... 1 2


External ID

Functional Category

Molecule Name

CFAMM00290453 CHEMBL200139 Bioactive AGN-PC-075YVZ
CFAMM00290450 DNC011713 Investigative Drug GT-2016

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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