CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3417
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1D Ligand 1-(2,5-dimethoxy-phenyl)-piperazine Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00290929 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Binder Superfamily 3
Class Class 1166

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Edrophonium Family 7 40
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Calcium-activated potassium channel subunit alpha-1 Ligand Chl... 2 15
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 3 67
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5... 4 24
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-(hexyl... 12 4
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
Nischarin inhibitor SureCN7818902 family 2 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
5-hydroxytryptamine receptor 1A ligand (1R,2R)-2-[4-(2,3-dihyd... 2 3
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Peptide deformylase inhibitor (2S)-N-(cyclopropylmethyl)-N-[2-... 1 0
Prelamin-A/C and Nonstructural protein 1 inhibitor CHEMBL14536... 1 2
Leukotriene A-4 hydrolase inhibitor AGN-PC-087BON family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00290929 DNC011794 Investigative Drug 1-(2,5-Dimethoxy-phenyl)-piperazine
CFAMM00290927 DNC011815 Investigative Drug 1-(2,5-Dimethoxy-4-methyl-phenyl)-piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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