CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3431
Family Name Angiotensin-converting enzyme Inhibitor N-carboxymethyl-n-cyclopentyl-phthalamic Acid Family
No. of Seeds 2 No. of Other Members 24
Family Centroid CFAMM00291178 Functional Category Investigative Drug with Natural Product
Superfamily Angiotensin-converting enzyme Inhibitor N-carboxymethyl-n-cyclopentyl-phthalamic Acid Superfamily
Class Class 1785

Cousin Family NamesSeedsMembers
B-lymphocyte antigen CD20 Inhibitor Bevacizumab+rituximab Family 1 5
CO-101 family 1 8
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-348926 Family 2 15
Glutamate receptor ionotropic, kainate 1 Ligand UBP-302 Family 1 5
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 2-[4-[[1-(2,... 2 7
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 13
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3... 6 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4346970 family 6 8
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4203288 family 2 2
Type-1B angiotensin II receptor ligand AGN-PC-074YOZ family 1 14


External ID

Functional Category

Molecule Name

CFAMM00291178 DNC011846 Investigative Drug N-Carboxymethyl-N-cyclopentyl-phthalamic acid
CFAMM00291185 DNC014867 Investigative Drug 2-(4-benzoylpiperidine-1-carbonyl)benzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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