CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3476
Family Name Reverse transcriptase Inhibitor 2-amino-6-(2-cyano-benzenesulfinyl)-benzonitrile Family
No. of Seeds 16 No. of Other Members 2
Family Centroid CFAMM00292196 Functional Category Investigative Drug
Superfamily Reverse transcriptase Binder Superfamily
Class Class 1052

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Reverse transcriptase Inhibitor 2-amino-6-(naphthalene-1-sulfo... 3 6
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Reverse transcriptase Inhibitor 2-amino-6-(3-bromo-benzenesulf... 5 1
Reverse transcriptase Inhibitor 2-amino-6-(3-chloro-phenylsulf... 6 4


External ID

Functional Category

Molecule Name

CFAMM00292202 CHEMBL299001 Bioactive 2-amino-6-(3,5-dimethylphenyl)sulfonylbenzonitrile
CFAMM00292201 DNC012062 Investigative Drug 2-Amino-6-(2-cyano-benzenesulfonyl)-benzonitrile
CFAMM00292208 DNC012060 Investigative Drug 2-Amino-6-(toluene-4-sulfonyl)-benzonitrile
CFAMM00292200 DNC012038 Investigative Drug 2-Amino-6-(3-cyano-phenylsulfanyl)-benzonitrile
CFAMM00292207 DNC012047 Investigative Drug 2-Amino-6-(2-fluoro-benzenesulfonyl)-benzonitrile
CFAMM00292199 DNC012059 Investigative Drug 2-Amino-6-benzenesulfonyl-benzonitrile
CFAMM00292206 DNC012048 Investigative Drug 2-Amino-6-m-tolylsulfanyl-benzonitrile
CFAMM00292212 DNC012037 Investigative Drug 2-Amino-6-(toluene-2-sulfonyl)-benzonitrile
CFAMM00292198 DNC012040 Investigative Drug 2-Amino-6-phenylsulfanyl-benzonitrile
CFAMM00292205 DNC012068 Investigative Drug 2-Amino-6-(3-cyano-benzenesulfonyl)-benzonitrile
CFAMM00292211 DNC012066 Investigative Drug 2-Amino-6-(toluene-3-sulfinyl)-benzonitrile
CFAMM00292197 DNC012035 Investigative Drug 2-Amino-6-p-tolylsulfanyl-benzonitrile
CFAMM00292204 DNC012039 Investigative Drug 2-Amino-6-(3-fluoro-phenylsulfanyl)-benzonitrile
CFAMM00292210 DNC012029 Investigative Drug 2-Amino-6-(2-cyano-phenylsulfanyl)-benzonitrile
CFAMM00292196 DNC012051 Investigative Drug 2-Amino-6-(2-cyano-benzenesulfinyl)-benzonitrile
CFAMM00292209 DNC012044 Investigative Drug 2-Amino-6-(toluene-3-sulfonyl)-benzonitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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