CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3486
Family Name Aminopeptidase N Inhibitor (1-amino-2-phenyl-ethyl)-phosphinic Acid Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00292290 Functional Category Investigative Drug with Natural Product
Superfamily Aminopeptidase N and Gamma-aminobutyric acid B receptor Binder Superfamily
Class Class 1610

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Amine oxidase [flavin-containing] B Inhibitor Phenelzine Family 7 15
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Gamma-aminobutyric acid B receptor Ligand Phaclofen Family 1 3
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Sphingosine 1-phosphate receptor 1 Ligand [3-(4-nonyl-benzylam... 9 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fl... 2 0
Prostatic acid phosphatase inhibitor Phosphonic acid, [1-napht... 1 0
Farnesyl pyrophosphate synthase inhibitor [1-hydroxy-3-[methyl... 4 1
(2S)-3-[[(S)-azaniumyl(phenyl)methyl]-oxidophosphoryl]-2-methy... 2 0


External ID

Functional Category

Molecule Name

CFAMM00292300 DNC012091 Investigative Drug (1-Amino-3-phenyl-propyl)-phosphinic acid
CFAMM00292290 DNC012083 Investigative Drug (1-Amino-2-phenyl-ethyl)-phosphinic acid
CFAMM00292296 DNC012104 Investigative Drug (Amino-phenyl-methyl)-phosphinic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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