CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family
No. of Seeds 1 No. of Other Members 42
Family Centroid CFAMM00188606 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Superfamily
Class Class 1548

Cousin Family NamesSeedsMembers
Kawain family 1 29
Glucokinase Inhibitor R7201 Family 22 105
Sodium-dependent noradrenaline transporter Inhibitor Polygalat... 2 87
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
4-hydroxyphenylpyruvate dioxygenase Inhibitor 3-hydroxy-4-phen... 1 8
Solute carrier family 52, riboflavin transporter, member 2 Inh... 1 7
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
Protein kinase C delta type and Protein kinase C beta type inh... 3 9
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Pol polyprotein inhibitor AGN-PC-01UWQ4 family 4 5
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Monoglyceride lipase inhibitor oxan-2-ylmethyl (E)-3-(4-phenyl... 1 2
Prostaglandin G/H synthase 2 inhibitor (2R,3S,5R)-2,3-bis(4-fl... 1 1
Neutrophil elastase inhibitor [4-oxo-6-(trityloxymethyl)pyran-... 1 0
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6


External ID

Functional Category

Molecule Name

CFAMM00188606 DNC000741 Investigative Drug Howiinol A (GHM-10)

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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