CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3504
Family Name Potassium voltage-gated channel subfamily KQT member 1 Ligand L-768673 Family
No. of Seeds 12 No. of Other Members 4
Family Centroid CFAMM00292869 Functional Category Investigative Drug
Superfamily Potassium voltage-gated channel subfamily KQT member 1 Ligand L-768673 Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Benzodiazepine receptor Ligand Clorazepate Family 2 3
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Benzodiazepine receptor ligand benzodiazepine derivative Fluni... 2 22
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
Cholecystokinin receptor type A Ligand L-708474 Family 14 82
Androgen receptor Ligand YM-175735 Family 30 129
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
D(2) dopamine receptor Ligand PD-168077 Family 6 5
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 5
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 5 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
C-C chemokine receptor type 3 ligand SureCN6703027 family 2 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Coagulation factor X and Trypsin-1 inhibitor 3-carbamimidoyl-N... 1 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 8 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 3 5
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 13
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 2 1
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 4
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-3-(3,4-dichlor... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 7 12
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 0
Growth hormone secretagogue receptor type 1 ligand SureCN77944... 1 2
Gastrin/cholecystokinin type B receptor ligand AGN-PC-01ZDS6 f... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 1
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 1 2
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-speci... 1 0
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 2 0
Coagulation factor VII inhibitor AGN-PC-0752PN family 1 1
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752NM... 2 3
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Putative NP ZINC55466512 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00292877 CHEMBL73699 Bioactive SureCN9867550
CFAMM00292868 CHEMBL135538 Bioactive AGN-PC-075MTI
CFAMM00292867 CHEMBL130093 Bioactive 4-[3-[[(2S)-3-(3,4-difluorophenyl)-2-methylpropanoyl]amino]-1-methyl-2-oxo-3H-1,4-benzodiazepin-5-yl]benzamide
CFAMM00292874 CHEMBL2092865 Bioactive SureCN9867693
CFAMM00292873 CHEMBL73483 Bioactive SureCN8977580
CFAMM00292865 CHEMBL132670 Bioactive (2S)-3-(3,4-difluorophenyl)-2-methyl-N-[(3S)-1-methyl-2-oxo-5-(5-oxo-7,8-dihydro-6H-naphthalen-2-yl)-3H-1,4-benzodiazepin-3-yl]propanamide
CFAMM00292864 CHEMBL423533 Bioactive (2S)-3-(3,4-difluorophenyl)-2-methyl-N-[(3S)-1-methyl-2-oxo-5-(1-oxo-2,3-dihydroinden-5-yl)-3H-1,4-benzodiazepin-3-yl]propanamide
CFAMM00292870 CHEMBL133820 Bioactive (2S)-3-(3,4-difluorophenyl)-2-methyl-N-[(3S)-1-methyl-2-oxo-5-(1-oxo-3,4-dihydro-2H-isoquinolin-6-yl)-3H-1,4-benzodiazepin-3-yl]propanamide
CFAMM00292869 DNC012138 Investigative Drug L-768673

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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