CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID352
Family Name Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family
No. of Seeds 6 No. of Other Members 17
Family Centroid CFAMM00188639 Functional Category Investigative Drug with Human Metabolite
Superfamily Histamine H1 receptor Ligand Chlophedianol Superfamily
Class Class 225

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Terfenadine Family 3 50
D(2) dopamine receptor Ligand Haloperidol Family 5 53
Histamine H1 receptor Ligand Clemastine Family 5 76
Delta-type opioid receptor Ligand Loperamide Family 8 55
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and D(2) dopamine receptor Ligand (+)-bu... 5 14
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 6
Glutamate receptor ionotropic, NMDA 3A and Glutamate receptor ... 2 1
Melanocortin receptor 4 and Melanocortin receptor 3 ligand Sur... 6 53
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
C-C chemokine receptor type 1 ligand SureCN7463390 family 1 6
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-04TFA0... 1 0
D(2) dopamine receptor and D(3) dopamine receptor ligand 4-(4-... 1 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 1
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 3 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Squalene synthase inhibitor 3-[2-(4-phenylphenyl)ethynyl]-1-az... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Cannabinoid receptor 2 ligand SureCN4472215 family 2 0
Nociceptin receptor and Mu-type opioid receptor ligand 8-[(2-c... 2 2
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 5
C-C chemokine receptor type 1 ligand SureCN9108276 family 1 0
C-C chemokine receptor type 1 ligand SureCN9108965 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00188646 CHEMBL356099 Bioactive AGN-PC-00GFTS
CFAMM00188639 DNC000751 Investigative Drug Hydroxamates
CFAMM00188629 DNC007730 Investigative Drug 1-benzhydryl-4-(4-chlorophenyl)piperidin-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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