CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3520
Family Name Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-trimethyl-ammonium Family
No. of Seeds 4 No. of Other Members 25
Family Centroid CFAMM00293168 Functional Category Investigative Drug
Superfamily Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-trimethyl-ammonium Superfamily
Class Class 2765

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Motilin receptor Ligand GSK962040 Family 30 457
Apoptosis regulator Bcl-2 Inhibitor MCI-186 Family 2 25
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-(2... 1 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 1,3,... 3 4
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phen... 4 8
Transient receptor potential cation channel subfamily V member... 6 33
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
Fatty-acid amide hydrolase 1 Inhibitor Phenyl-1,4-bismaleimide... 1 5
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Sodiu... 2 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 31
Tyrosinase Inhibitor 1-hydroxy-3-phenylurea Family 2 10
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 2
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
5-hydroxytryptamine receptor 2B and Prostaglandin G/H synthase... 1 16
Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand ... 3 13
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
5-hydroxytryptamine receptor 4 ligand 2-PIPERIDIN-1-YLETHYL PH... 1 3
Lysophosphatidic acid receptor 2 and Lysophosphatidic acid rec... 1 0
Monoglyceride lipase and Fatty-acid amide hydrolase 1 inhibito... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00293162 CHEMBL342537 Bioactive AGN-PC-075R1E
CFAMM00293160 CHEMBL126487 Bioactive AGN-PC-00GVDZ
CFAMM00293159 CHEMBL147334 Bioactive AGN-PC-09QLY2
CFAMM00293168 DNC012243 Investigative Drug (3-Hydroxy-2-methyl-phenyl)-trimethyl-ammonium

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26823 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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