CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3525
Family Name Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand L-698532 Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00293224 Functional Category Investigative Drug with Human Metabolite
Superfamily Cyclooxygenase and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 448

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Serum albumin Inhibitor Iodipamide Family 2 23
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Dihydroorotate dehydrogenase Inhibitor 2-(2-bromo-2-naphthamid... 1 2
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Glutamate receptor ionotropic, kainate 1 Ligand 2-(3-(3-bromop... 2 1
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Bifunctional epoxide hydrolase 2 Inhibitor 4-(3-adamantan-1-yl... 3 12
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 5
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 3
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 6 13
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Prostaglandin E synthase inhibitor 4-chloro-2-[[1,3-dioxo-2-(1... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Tankyrase-2 inhibitor 3-chloro-4-(4-methyl-2-oxo-1H-quinolin-7... 1 2
Reverse transcriptase/RNaseH inhibitor 6-CHLORO-4-(CYCLOHEXYLO... 2 0
Holo-[acyl-carrier-protein] synthase inhibitor AGN-PC-00CGZN f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00293236 DNC012266 Investigative Drug 5,7-Dichloro-4-hydroxy-3-phenyl-1H-quinolin-2-one
CFAMM00293224 DNC012257 Investigative Drug L-698532
CFAMM00293242 DNC012917 Investigative Drug 3-phenyl-4-hydroxyquinolin-2(1H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42757 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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