CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3538
Family Name Reverse transcriptase Inhibitor LY-73497 Family
No. of Seeds 14 No. of Other Members 5
Family Centroid CFAMM00293353 Functional Category Investigative Drug
Superfamily Reverse transcriptase Binder Superfamily 3
Class Class 2802

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthi... 4 7
Arachidonate 5-lipoxygenase Inhibitor N-(thiazol-2-yl)benzamid... 3 53
Arachidonate 5-lipoxygenase Inhibitor 2-phenyl-n-(thiazol-2-yl... 3 27
Reverse transcriptase Inhibitor PT-316 Family 8 2
Histamine H3 receptor ligand N-methyl-3-phenyl-N-[2-[2-(4-prop... 1 4


External ID

Functional Category

Molecule Name

CFAMM00293354 DNC012331 Investigative Drug PT-308
CFAMM00293362 DNC012570 Investigative Drug 1-(1-Phenyl-propyl)-3-thiazol-2-yl-thiourea
CFAMM00293353 DNC012317 Investigative Drug LY-73497
CFAMM00293368 DNC012369 Investigative Drug PT-322
CFAMM00293361 DNC012341 Investigative Drug PT-312
CFAMM00293352 DNC012355 Investigative Drug PT-307
CFAMM00293367 DNC012343 Investigative Drug PT-302
CFAMM00293359 DNC012325 Investigative Drug PT-306
CFAMM00293351 DNC012356 Investigative Drug PT-309
CFAMM00293358 DNC012626 Investigative Drug 1-Thiazol-2-yl-3-(2-p-tolyl-ethyl)-thiourea
CFAMM00293365 DNC012308 Investigative Drug 1-Thiazol-2-yl-3-(2-o-tolyl-ethyl)-thiourea
CFAMM00293356 DNC012310 Investigative Drug 1-Benzyl-3-thiazol-2-yl-thiourea
CFAMM00293364 DNC012307 Investigative Drug 1-(3-Phenyl-propyl)-3-thiazol-2-yl-thiourea
CFAMM00293355 DNC012315 Investigative Drug 1-(2-Phenyl-propyl)-3-thiazol-2-yl-thiourea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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