CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3555
Family Name Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand 3-hydroxy-1h-benzo[b]azepine-2,5-dione Family
No. of Seeds 6 No. of Other Members 13
Family Centroid CFAMM00293492 Functional Category Investigative Drug with Natural Product
Superfamily Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Binder Superfamily
Class Class 2806

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Transient receptor potential cation channel subfamily V member... 6 33
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 5
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 0
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 8 3
Androgen receptor ligand 6-[bis(2,2,2-trifluoroethyl)amino]-4-... 1 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 2
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 7 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00293478 DNC012396 Investigative Drug 3-Hydroxy-7-nitro-1H-benzo[b]azepine-2,5-dione
CFAMM00293485 DNC012379 Investigative Drug 3-Hydroxy-6-methyl-1H-benzo[b]azepine-2,5-dione
CFAMM00293483 DNC012373 Investigative Drug 8-Ethyl-3-hydroxy-1H-benzo[b]azepine-2,5-dione
CFAMM00293492 DNC012386 Investigative Drug 3-Hydroxy-1H-benzo[b]azepine-2,5-dione
CFAMM00293482 DNC012400 Investigative Drug 3-Hydroxy-8-methyl-1H-benzo[b]azepine-2,5-dione
CFAMM00293480 DNC012390 Investigative Drug 8-Fluoro-3-hydroxy-1H-benzo[b]azepine-2,5-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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