CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3577
Family Name Prostaglandin G/H synthase 1 Inhibitor 2-(3'-ethylsulfanyl-biphenyl-4-yl)-propionic Acid Family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00293891 Functional Category Investigative Drug
Superfamily Aldose reductase Inhibitor Sulindac Superfamily
Class Class 340

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Prostaglandin G/H synthase 1 Inhibitor Suprofen Family 4 52
CPI-613 family 4 35
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Leukotriene B4 receptor 1 ligand 2,2-dimethyl-7-[3-(3-phenylpr... 2 10
Retinal dehydrogenase 1 and Microtubule-associated protein tau... 1 7


External ID

Functional Category

Molecule Name

CFAMM00293891 DNC012493 Investigative Drug 2-(3'-Ethylsulfanyl-biphenyl-4-yl)-propionic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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