CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3607
Family Name 5-hydroxytryptamine receptor 1A Ligand CP-293019 Family
No. of Seeds 9 No. of Other Members 24
Family Centroid CFAMM00294549 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A Ligand CP-293019 Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Histamine H1 receptor Ligand Mepyramine Family 5 65
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Melanin-concentrating hormone receptor 1 Ligand NGD-4715 Family 1 1
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
AP26113 family 16 90
SB1518 family 7 103
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 2 3
Reverse transcriptase Inhibitor UK-129485 Family 23 221
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Deoxycytidine kinase inhibitor AGN-PC-07Z9C8 family 5 3
Deoxycytidine kinase inhibitor AGN-PC-07Z9GO family 10 2
Deoxycytidine kinase inhibitor 2-[1-[6-(2-chlorophenoxy)pyrimi... 2 3
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 4 2
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Transient receptor potential cation channel subfamily V member... 2 4
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor 1-... 1 3
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 1 1
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 2 5
Beta-secretase 1 and Beta-secretase 2 inhibitor AGN-PC-076LAV ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00294522 CHEMBL159903 Bioactive SureCN5403278
CFAMM00294537 CHEMBL1081901 Bioactive AGN-PC-07Z9EF
CFAMM00294528 CHEMBL162265 Bioactive AGN-PC-03IVAE
CFAMM00294520 CHEMBL166269 Bioactive SureCN5414323
CFAMM00294518 CHEMBL163009 Bioactive SureCN5402861
CFAMM00294548 CHEMBL1940417 Bioactive 2-[4-[3-(4-fluorophenoxy)propyl]piperazin-1-yl]pyrimidine
CFAMM00294517 CHEMBL165504 Bioactive (7S,9aS)-7-(phenoxymethyl)-2-pyrimidin-2-yl-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
CFAMM00294549 DNC012679 Investigative Drug CP-293019

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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