CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID361
Family Name Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-dione Family
No. of Seeds 5 No. of Other Members 35
Family Centroid CFAMM00188820 Functional Category Investigative Drug with Human Metabolite
Superfamily Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-dione Superfamily
Class Class 1554

Cousin Family NamesSeedsMembers
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Cellular tumor antigen p53 inhibitor CHEMBL1554992 family 1 0
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Caspase-3 and Caspase-7 inhibitor Isatin Sulfonamide 34 family 24 51
Caspase-7 and Caspase-3 inhibitor 1-(3-fluorobutyl)-5-[(2S)-2-... 10 32
Caspase-3 and Caspase-7 inhibitor 1-[[4-[tert-butyl(dimethyl)s... 2 0
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltra... 5 10
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Caspase-7 and Caspase-3 inhibitor 1-[[4-(1-fluoro-2-hydroxyeth... 2 0
Caspase-3 inhibitor SureCN5337317 family 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00188844 DNC000797 Investigative Drug Indirubin-5-sulfonate
CFAMM00188828 DNC009873 Investigative Drug 5-(piperidin-1-ylsulfonyl)indoline-2,3-dione
CFAMM00188820 DNC009876 Investigative Drug 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-dione
CFAMM00188834 DNC009875 Investigative Drug 5-(azepan-1-ylsulfonyl)indoline-2,3-dione
CFAMM00188833 DNC009874 Investigative Drug 5-(azetidin-1-ylsulfonyl)indoline-2,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543