CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3613
Family Name Aldose reductase Inhibitor (6-hydroxy-2-oxo-2h-quinolin-1-yl)-acetic Acid Family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00294609 Functional Category Investigative Drug with Natural Product
Superfamily Oestrogen receptor and Estrogen receptor beta Binder Superfamily 2
Class Class 1996

Cousin Family NamesSeedsMembers
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor 5... 4 24
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Angiotensin-converting enzyme inhibitor 1-(3-benzoylsulfanyl-2... 4 1


External ID

Functional Category

Molecule Name

CFAMM00294612 DNC012708 Investigative Drug (8-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid
CFAMM00294610 DNC012707 Investigative Drug (6-Methoxy-2-oxo-2H-quinolin-1-yl)-acetic acid
CFAMM00294609 DNC012711 Investigative Drug (6-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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