CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3616
Family Name Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand 4,5,7-trichloro-3-hydroxy-1h-quinolin-2-one Family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00294660 Functional Category Investigative Drug
Superfamily Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand 4,5,7-trichloro-3-hydroxy-1h-quinolin-2-one Superfamily
Class Class 2826

Cousin Family NamesSeedsMembers
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Transient receptor potential cation channel subfamily V member... 6 33
Cruzipain Inhibitor N1,n4-bis(5-chloro-2-methylphenyl)succinam... 1 5
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 8 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00294654 CHEMBL495187 Bioactive 5-chloro-3-hydroxy-1H-quinolin-2-one
CFAMM00294660 DNC012720 Investigative Drug 4,5,7-Trichloro-3-hydroxy-1H-quinolin-2-one
CFAMM00294659 DNC012723 Investigative Drug 4-Bromo-5,7-dichloro-3-hydroxy-1H-quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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