CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3619
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor 1-(3,4-dichloro-phenyl)-3-methylamino-indan-5-ol Family
No. of Seeds 10 No. of Other Members 9
Family Centroid CFAMM00294694 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor 1-(3,4-dichloro-phenyl)-3-methylamino-indan-5-ol Superfamily
Class Class 1325

Cousin Family NamesSeedsMembers
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
CORT-108297 family 46 44
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TF5... 1 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 1 1
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (2R,... 1 0
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Transporter and Sodium-dependent serotonin transporter inhibit... 1 0
Sodium-dependent dopamine transporter and Transporter inhibito... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00294698 CHEMBL543372 Bioactive (1R,3S)-3-(3,4-dichlorophenyl)-6-methoxy-N-methyl-2,3-dihydro-1H-inden-1-amine;hydrochloride
CFAMM00294691 CHEMBL53837 Bioactive AGN-PC-00MZRM
CFAMM00294690 CHEMBL537996 Bioactive AGN-PC-07BZFX
CFAMM00294703 CHEMBL300019 Bioactive AGN-PC-008O2D
CFAMM00294686 CHEMBL543688 Bioactive (1R)-3-(3,4-dichlorophenyl)-6-methoxy-N-methyl-2,3-dihydro-1H-inden-1-amine;hydrochloride
CFAMM00294700 CHEMBL89142 Bioactive (1R,3S)-1-(3,4-dichlorophenyl)-3-(methylamino)-2,3-dihydro-1H-inden-5-ol
CFAMM00294704 DNC012732 Investigative Drug 1-(3,4-Dichloro-phenyl)-3-diethylamino-indan-5-ol
CFAMM00294694 DNC012729 Investigative Drug 1-(3,4-Dichloro-phenyl)-3-methylamino-indan-5-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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