CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3625
Family Name Delta-type opioid receptor and Kappa-type opioid receptor Ligand SN-23 Family
No. of Seeds 38 No. of Other Members 35
Family Centroid CFAMM00294781 Functional Category Investigative Drug
Superfamily Delta-type opioid receptor and Kappa-type opioid receptor Ligand SN-23 Superfamily
Class Class 770

Cousin Family NamesSeedsMembers
Histamine N-methyltransferase inhibitor aminoquinoline Amodiaq... 8 23
Phospholipase A2 Inhibitor Quinacrine Family 13 95
DNA Binder Elliptinium Acetate Family 11 116
Citric Acid family 2 58
Tumor necrosis factor receptor superfamily member 5 Ligand Dac... 48 288
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
E3 ubiquitin-protein ligase Mdm2 Inhibitor NSC-66811 Family 4 27
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 9 12
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 6 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 1
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Glucocorticoid receptor ligand 4-fluoro-2-[5,5,5-trifluoro-4-h... 3 9
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 18
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Androgen receptor ligand (6R,7S)-6-ethyl-7-methyl-4-(trifluoro... 22 29
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Delta-type opioid receptor and Kappa-type opioid receptor liga... 4 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Androgen receptor ligand SureCN1771931 family 5 3
Transient receptor potential cation channel subfamily V member... 1 5
Estrogen receptor beta and Estrogen receptor ligand 2-fluoro-4... 1 0
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
C5a anaphylatoxin chemotactic receptor 1 ligand 2-(2,6-diethyl... 3 5
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aR... 3 6
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PJ... 4 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aS... 2 1
Kinesin-like protein KIF11 inhibitor AGN-PC-07R5ZC family 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00294811 CHEMBL2147904 Bioactive CHEMBL2147904
CFAMM00294762 CHEMBL1929364 Bioactive CHEMBL1929364
CFAMM00294790 CHEMBL2147922 Bioactive CHEMBL2147922
CFAMM00294768 CHEMBL226166 Bioactive CHEMBL226166
CFAMM00294810 CHEMBL2147905 Bioactive CHEMBL2147905
CFAMM00294761 CHEMBL1929369 Bioactive CHEMBL1929369
CFAMM00294803 CHEMBL2147930 Bioactive CHEMBL2147930
CFAMM00294809 CHEMBL2147906 Bioactive CHEMBL2147906
CFAMM00294823 CHEMBL2147913 Bioactive CHEMBL2147913
CFAMM00294760 CHEMBL1929368 Bioactive CHEMBL1929368
CFAMM00294773 CHEMBL1270382 Bioactive CHEMBL1270382
CFAMM00294788 CHEMBL2147920 Bioactive CHEMBL2147920
CFAMM00294815 CHEMBL2147908 Bioactive CHEMBL2147908
CFAMM00294829 CHEMBL1270475 Bioactive CHEMBL1270475
CFAMM00294766 CHEMBL1929362 Bioactive CHEMBL1929362
CFAMM00294808 CHEMBL2147907 Bioactive CHEMBL2147907
CFAMM00294822 CHEMBL2147911 Bioactive CHEMBL2147911
CFAMM00294772 CHEMBL1270383 Bioactive CHEMBL1270383
CFAMM00294787 CHEMBL2147921 Bioactive CHEMBL2147921
CFAMM00294801 CHEMBL1270185 Bioactive CHEMBL1270185
CFAMM00294765 CHEMBL1929367 Bioactive CHEMBL1929367
CFAMM00294828 CHEMBL1270474 Bioactive CHEMBL1270474
CFAMM00294821 CHEMBL2147910 Bioactive CHEMBL2147910
CFAMM00294758 CHEMBL375504 Bioactive CHEMBL375504
CFAMM00294771 CHEMBL2147909 Bioactive CHEMBL2147909
CFAMM00294785 CHEMBL2147928 Bioactive CHEMBL2147928
CFAMM00294820 CHEMBL1270282 Bioactive CHEMBL1270282
CFAMM00294806 CHEMBL1270573 Bioactive CHEMBL1270573
CFAMM00294770 CHEMBL552308 Bioactive SN-28
CFAMM00294784 CHEMBL2147929 Bioactive CHEMBL2147929
CFAMM00294763 CHEMBL1929365 Bioactive CHEMBL1929365
CFAMM00294781 DNC014084 Investigative Drug SN-23
CFAMM00294780 DNC014085 Investigative Drug SN-28
CFAMM00294759 DNC012751 Investigative Drug SB-213698
CFAMM00294779 DNC014083 Investigative Drug SN-11

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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