CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3629
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor ONO-3805 Family
No. of Seeds 8 No. of Other Members 39
Family Centroid CFAMM00294888 Functional Category Investigative Drug with Natural Product
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor ONO-3805 Superfamily
Class Class 2482

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Histamine H1 receptor Ligand Tranilast Family 5 125
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
Receptor tyrosine-protein kinase erbB-2 Inhibitor Mini-antibod... 1 0
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Glycogen phosphorylase, muscle form Inhibitor 4-{2-[(3-nitrobe... 1 12
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Integrin beta-1 and Integrin alpha-4 inhibitor 3-[4-[(2,6-dich... 5 6
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Prostaglandin D2 receptor ligand 2-[4-chloro-3-[[4-[[(3R)-2,3-... 2 0
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 3 1
Capsid scaffolding protein inhibitor AC1MHP20 family 3 3
Retinoic acid receptor RXR-gamma and Retinoic acid receptor RX... 3 36
Mitogen-activated protein kinase 14 inhibitor AGN-PC-00A4QT fa... 2 0
Mitogen-activated protein kinase 14 inhibitor ITX 5061 free ba... 2 3
Mitogen-activated protein kinase 14 inhibitor AGN-PC-04UTCQ fa... 2 1
Targeted effector protein and Tyrosine-protein phosphatase non... 2 2
Acyl-CoA:cholesterol acyltransferase inhibitor KF 17828 family 4 11
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8797384 f... 1 0
Leukotriene B4 receptor 1 ligand 4-methoxy-3-[[(E)-3-(4-phenyl... 2 10
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Mitogen-activated protein kinase 14 inhibitor SureCN1600485 fa... 1 1
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00294899 CHEMBL1819608 Bioactive 2-[3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00294903 CHEMBL1819613 Bioactive 2-[2-methyl-5-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00294911 CHEMBL1915674 Bioactive 2-[3-[[2,5-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-4-methylphenyl]acetic acid
CFAMM00294902 CHEMBL1819612 Bioactive 2-[3-methyl-5-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00294910 CHEMBL1915675 Bioactive 2-[3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-4-methylphenyl]acetic acid
CFAMM00294901 CHEMBL1819611 Bioactive 2-[4-methyl-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00294916 CHEMBL1915672 Bioactive 2-[3-[[2,6-dimethyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acid
CFAMM00294888 DNC012759 Investigative Drug ONO-3805

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26224 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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