CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3633
Family Name Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor Ligand 1,2,3,4-tetrahydro-benzo[h]isoquinolin-8-ol Family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00295034 Functional Category Investigative Drug
Superfamily Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 2
Class Class 1891

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Kappa-type opioid receptor Ligand Dezocine Family 36 46
D(2) dopamine receptor Ligand Quinagolide Family 2 0
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand Ezlopitant Family 10 207
CORT-108297 family 46 44
Dapoxetine family 3 40
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Amine oxidase [flavin-containing] B Inhibitor 5-hydroxy-n-prop... 3 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
5-hydroxytryptamine receptor 1A Ligand 9-methoxy-1,2,3,4-tetra... 7 10
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
D(2) dopamine receptor and D(1A) dopamine receptor Ligand SK&F... 8 8
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Tubulin beta chain Inhibitor Colchinol Family 3 109
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TFC... 2 7
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-01Z... 2 4
D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,... 3 2
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Carbonic anhydrase 14 and Carbonic anhydrase 9 inhibitor 1-(4-... 2 3
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 5
Alpha-2A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00295035 DNC012793 Investigative Drug 1,2,3,4-Tetrahydro-isoquinolin-7-ol
CFAMM00295034 DNC012768 Investigative Drug 1,2,3,4-Tetrahydro-benzo[h]isoquinolin-8-ol
CFAMM00295038 DNC013487 Investigative Drug 1,2,3,7,12,12a-hexahydro-1-aza-pleiaden-5-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543