CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3654
Family Name Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4-bromo-3-phenoxy-benzoylamino)-benzoic Acid Family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00295529 Functional Category Investigative Drug with Natural Product
Superfamily Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4-bromo-3-phenoxy-benzoylamino)-benzoic Acid Superfamily
Class Class 2835

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Substance-K receptor Ligand SLV-332 Family 1 1
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Receptor tyrosine-protein kinase erbB-2 Inhibitor Mini-antibod... 1 0
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
MO15-related protein kinase Pfmrk Inhibitor 3-[3-(2-hydroxy-et... 1 6
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Transient receptor potential cation channel subfamily V member... 1 2
3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 2-[[4-(4... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 8 1
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 2 3
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1
Capsid scaffolding protein inhibitor AC1MHP20 family 3 3
NS5B protein inhibitor AC1NQV11 family 4 17
Follicle-stimulating hormone receptor ligand (1-acetyl-2,2,4-t... 1 2
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 0
Vascular endothelial growth factor receptor 2 ligand CHEMBL197... 1 1
Major prion protein and Microtubule-associated protein tau inh... 2 10
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 1
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 2 1
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3
2-carboxy-5-[[(E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl]amino]p... 1 0
methyl 2-[(7-bromo-1-benzoxepine-4-carbonyl)amino]benzoate NP ... 1 0
Putative NP ZINC08880095 Family 2 0
3,5-bis[[2-(4-methoxyphenoxy)acetyl]amino]benzoate NP Agn-pc-0... 1 1
Putative NP ZINC17112928 Family 5 0
bromo-N-[2-(4-tert-butylphenyl)-4-oxochromen-7-yl]benzamide NP... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00295523 DNC012892 Investigative Drug 2-Hydroxy-6-(3-phenoxy-benzoylamino)-benzoic acid
CFAMM00295529 DNC012844 Investigative Drug 2-(4-Bromo-3-phenoxy-benzoylamino)-benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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