CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3673
Family Name Voltage-dependent calcium channel gamma-1 subunit Ligand 4-(3,4-dimethylbenzylthio)-2-aminobutanoic Acid Family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00295953 Functional Category Investigative Drug
Superfamily Voltage-dependent calcium channel gamma-1 subunit Ligand 4-(3,4-dimethylbenzylthio)-2-aminobutanoic Acid Superfamily
Class Class 2318

Cousin Family NamesSeedsMembers
Neprilysin Inhibitor Thiorphan Family 41 68
Voltage-dependent calcium channel gamma-1 subunit Ligand (s)-2... 6 31
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 2 1
Kinesin-like protein KIF11 inhibitor 1-[4-[2-aminoethylsulfany... 2 4
Kinesin-like protein KIF11 inhibitor (2R)-2-amino-3-tritylsulf... 1 0
Kinesin-like protein KIF11 inhibitor methyl (2S)-2-[[(2R)-2-am... 1 1


External ID

Functional Category

Molecule Name

CFAMM00295959 CHEMBL2325410 Bioactive (2R)-2-amino-3-[(3,4-dimethylphenyl)-diphenylmethyl]sulfanylpropanoic acid
CFAMM00295951 CHEMBL2325412 Bioactive (2R)-2-amino-3-[(3-ethyl-4-methylphenyl)-diphenylmethyl]sulfanylpropanoic acid
CFAMM00295947 DNC012946 Investigative Drug 2-amino-4-(2-methyl-benzylsulfanyl)-butyric acid
CFAMM00295953 DNC012938 Investigative Drug 4-(3,4-dimethylbenzylthio)-2-aminobutanoic acid
CFAMM00295958 DNC012937 Investigative Drug 4-(3,5-dimethylbenzylthio)-2-aminobutanoic acid
CFAMM00295952 DNC012943 Investigative Drug 4-(4-tert-butylbenzylthio)-2-aminobutanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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