CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3684
Family Name Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Ligand H-gly-d-dmp-glu-oh Family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00296097 Functional Category Investigative Drug with Human Metabolite
Superfamily Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B Binder Superfamily 2
Class Class 598

Cousin Family NamesSeedsMembers
Peptidyl-prolyl cis-trans isomerase A and Peptidyl-prolyl cis-... 2 35
Carbamoyl-phosphate synthase [ammonia], mitochondrial Inhibito... 5 13
Glutamine receptor Ligand L-alanyl-l-glutamine Family 3 101
Thymalfasin family 10 31
D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-a... 5 89
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alp... 4 18
Sodium/glucose cotransporter 1 Inhibitor Qcpac Family 4 7
Sodium/glucose cotransporter 1 Inhibitor Qspac Family 3 8
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 1 0
Angiotensin-converting enzyme inhibitor AC1L5A5N family 1 1
Nucleotide-binding oligomerization domain-containing protein 1... 14 7
Nucleotide-binding oligomerization domain-containing protein 1... 1 0
Bloom syndrome protein and Tyrosyl-DNA phosphodiesterase 1 inh... 1 1
Angiotensin-converting enzyme inhibitor 1-[2-[[carboxy-[1-(car... 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor Gl... 1 0
Prelamin-A/C and DNA-(apurinic or apyrimidinic site) lyase inh... 1 2
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[(2-carboxyacety... 1 0
Renin inhibitor (2S)-1-[(2R)-4-(hydroxyamino)-2-methyl-4-oxobu... 2 0
Peptides Metabolite Valyl-Hydroxyproline Family 1 1
Peptides Metabolite L-prolyl-L-glycine Family 1 3
carboxylate NP (r)-tert-butyl 2-(((r)-1-((2-methoxy-2-oxoethyl... 2 3


External ID

Functional Category

Molecule Name

CFAMM00296105 CHEMBL197208 Bioactive (2R)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]pentanedioic acid
CFAMM00296107 DNC012978 Investigative Drug Gly-Amp-Glu
CFAMM00296096 DNC013063 Investigative Drug H-Gly-PMe-Glu-OH
CFAMM00296106 DNC012979 Investigative Drug Nle-Pro-Glu
CFAMM00296095 DNC013062 Investigative Drug H-Gly-dmP-Glu-OH
CFAMM00296097 DNC013061 Investigative Drug H-Gly-D-dmP-Glu-OH

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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