CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3696
Family Name Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]carbazol-9-ol Family
No. of Seeds 7 No. of Other Members 9
Family Centroid CFAMM00296381 Functional Category Investigative Drug
Superfamily DNA Binder Elliptinium Acetate Superfamily
Class Class 770

Cousin Family NamesSeedsMembers
DNA Binder Elliptinium Acetate Family 11 116
Citric Acid family 2 58
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Oestrogen receptor Ligand 3-chloro-2-(4-hydroxyphenyl)-2h-inda... 2 2
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Estrogen receptor ligand 4-[3,5-bis(4-hydroxyphenyl)-1-propylp... 1 0
Transient receptor potential cation channel subfamily V member... 1 5
Estrogen receptor beta and Estrogen receptor ligand 2-fluoro-4... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Estrogen receptor and Estrogen receptor beta ligand SureCN6841... 2 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 0
Aldose reductase and Aldo-keto reductase family 1 member B10 i... 1 2
Proto-oncogene tyrosine-protein kinase Src and cAMP-dependent ... 2 0
Proto-oncogene tyrosine-protein kinase Src and cAMP-dependent ... 2 0
Proto-oncogene tyrosine-protein kinase Src and cAMP-dependent ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00296375 CHEMBL2178797 Bioactive 4-[3,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
CFAMM00296374 CHEMBL2178795 Bioactive 4-[4,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]phenol
CFAMM00296380 CHEMBL2179256 Bioactive 4-[2,5-bis(4-hydroxyphenyl)-1-propylpyrrol-3-yl]-3-fluorophenol
CFAMM00296384 CHEMBL2179251 Bioactive 4-[4,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
CFAMM00296377 CHEMBL2178793 Bioactive 4-[4,5-bis(2-fluoro-4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
CFAMM00296376 CHEMBL2178792 Bioactive 3-fluoro-4-[5-(2-fluoro-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-1-propylpyrrol-2-yl]phenol
CFAMM00296381 DNC013034 Investigative Drug 11-methyl-6,11-dihydro-5H-benzo[a]carbazol-9-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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