CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3699
Family Name Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pro-ala-thr(obzl)-gly Family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00296397 Functional Category Investigative Drug
Superfamily Neurotensin receptor type 1 and Ceramide glucosyltransferase Binder Superfamily
Class Class 858

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Trypsin inhibitor polypeptide Aprotinin Family 7 68
Oxytocin receptor Ligand Oxytocin Family 30 182
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
HIV-1 protease Inhibitor Lopinavir Family 4 25
Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Plitidepsin family 15 5
Flovagatran family 12 546
Tryptase Inhibitor APC-366 Family 2 12
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU84687 F... 2 14
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Proto-oncogene tyrosine-protein kinase Src Inhibitor Y-c[d-pen... 20 66
Somatostatin receptor type 1 Ligand Des-aa1,2,5-[(nalphame)lys... 16 11
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-tyr(me)-agly-i... 2 1
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-isopropyl Estrad... 3 0
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 8
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 4
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Vasopressin V1a receptor Ligand Vasopressin Analogue Family 4 3
Pol polyprotein inhibitor 180968-31-4 family 8 13
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (3S,6R,11R,14S)... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 6 1
Cathepsin B and Calpain-2 catalytic subunit inhibitor AGN-PC-0... 2 2
Tyrosine--tRNA ligase, cytoplasmic inhibitor (2S)-2-[[(2S)-2-a... 5 2
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic rec... 5 0
Pol polyprotein inhibitor AC1LADQG family 7 1
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 6
Pol polyprotein inhibitor MDL 74538 family 11 1
Melanocyte-stimulating hormone receptor and Melanocortin recep... 3 16
Oxytocin receptor ligand (2S)-N-[(2R)-1-[2-[[5-amino-1-[[1-ami... 4 0
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Mu-type opioid receptor ligand 4-[(2S)-3-[[(2S)-1-(4-hydroxyph... 2 6
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
C-X-C chemokine receptor type 4 ligand CHEMBL2372990 family 3 0
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4R)-4-(3-hydroxyp... 4 1
Renin inhibitor (3S,6R)-6-(cyclohexylmethyl)-7-hydroxy-7-[[(2S... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 3
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Neprilysin inhibitor benzyl (2S)-3-(4-hydroxyphenyl)-2-[[2-(su... 1 1
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Prothrombin inhibitor (2S)-1-[(2R)-2-amino-2-cyclohexylacetyl]... 2 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Gonadotropin-releasing hormone receptor ligand (3R,6S,12S,15S,... 1 0
Somatostatin receptor type 2 and Somatostatin receptor type 3 ... 2 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 2
Signal transducer and activator of transcription 3 inhibitor [... 7 25
Signal transducer and activator of transcription 3 inhibitor [... 3 1
Pol polyprotein inhibitor AC1MHYEO family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00296398 DNC013048 Investigative Drug bip-tyr-thr-ala-pro-phe
CFAMM00296397 DNC013050 Investigative Drug bip-tyr-thr-pro-ala-thr(obzl)-gly
CFAMM00296396 DNC013051 Investigative Drug bip-tyr-thr-pro-lys-thr(obzl)-gly
CFAMM00296395 DNC013052 Investigative Drug bip-tyr(3bzl)-thr-pro-lys-thr
CFAMM00296394 DNC013054 Investigative Drug bip-tyr-ala-pro-lys-thr(obzl)-gly
CFAMM00296399 DNC013049 Investigative Drug bip-tyr-thr-pro-thr(obzl)-gly

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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