CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3713
Family Name Delta-type opioid receptor and Mu-type opioid receptor Ligand H-dmt-tic-lys(z)-nh-ch2-ph Family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00296498 Functional Category Investigative Drug
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily
Class Class 1664

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Thymopentin family 20 133
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Tryptase Inhibitor APC-366 Family 2 12
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU84687 F... 2 14
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Proto-oncogene tyrosine-protein kinase Src Inhibitor Y-c[d-pen... 20 66
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 9 43
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 3 0
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 4
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Pol polyprotein inhibitor 180968-31-4 family 8 13
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Growth factor receptor-bound protein 2 ligand (3-aminophenyl)m... 5 13
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 2
Type-2 angiotensin II receptor ligand SureCN244657 family 7 11
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
Growth hormone secretagogue receptor type 1 ligand 2-benzylsul... 2 0
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Pol polyprotein inhibitor MDL 74538 family 11 1
NS3 inhibitor Proline-Based Macrocycle 24 family 6 6
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Prothrombin inhibitor (2S)-1-[(2R)-2-amino-2-cyclohexylacetyl]... 2 1
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(3-hydr... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 2
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 5 2
Histone deacetylase 8 and Histone deacetylase 6 inhibitor (3S)... 4 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00296501 CHEMBL365762 Bioactive (2S)-2-[[(2S)-2-[[2-[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-3-phenylpropanoyl]amino]-6-(phenylmethoxycarbonylamino)hexanoic acid
CFAMM00296499 CHEMBL232812 Bioactive benzyl N-[(2S)-6-[[(3S)-2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-1-(benzylamino)-1-oxohexan-2-yl]carbamate
CFAMM00296505 CHEMBL190543 Bioactive benzyl N-[(5S)-6-amino-5-[[(2S)-2-[[2-[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-3-phenylpropanoyl]amino]-6-oxohexyl]carbamate
CFAMM00296498 DNC013101 Investigative Drug H-Dmt-Tic-Lys(Z)-NH-CH2-Ph
CFAMM00296503 DNC013116 Investigative Drug H-Dmt-Tic-Lys(Z)-NH-Ph

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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