CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID374
Family Name DNA topoisomerase 1 Inhibitor KT6006 Family
No. of Seeds 3 No. of Other Members 53
Family Centroid CFAMM00189453 Functional Category Investigative Drug
Superfamily DNA topoisomerase 1 Inhibitor KT6006 Superfamily
Class Class 1562

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
High affinity nerve growth factor receptor and Mitogen-activat... 2 7
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Renin inhibitor SureCN1144364 family 3 15
DNA topoisomerase 1 inhibitor EDOTECARIN family 3 35
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family 1 2
Wee1-like protein kinase and Serine/threonine-protein kinase C... 3 51
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00189437 CHEMBL83790 Bioactive CHEMBL83790
CFAMM00189453 DNC000840 Investigative Drug KT6006

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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