CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3761
Family Name Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methylquinolin-7-yl)benzonitrile Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00297484 Functional Category Investigative Drug
Superfamily Metabotropic glutamate receptor 5 and E3 ubiquitin-protein ligase Mdm2 Binder Superfamily
Class Class 1788

Cousin Family NamesSeedsMembers
Phospholipase A2 Inhibitor Quinacrine Family 13 95
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Food vacuoles Inhibitor Mefloquine Family 2 25
Citric Acid family 2 58
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU79072 F... 1 2
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-((3-methox... 3 9
Arachidonate 12-lipoxygenase, 12S-type Inhibitor NSC-125034 Fa... 1 0
Indoleamine 2,3-dioxygenase 1 Inhibitor 5-aminoquinolin-8-ol F... 3 16
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-... 3 6
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Estrogen receptor beta and Estrogen receptor ligand 2-fluoro-4... 1 0
Steroid hormone receptor ERR1 and Steroid hormone receptor ERR... 1 4
Estrogen receptor and Estrogen receptor beta ligand SureCN6841... 2 5
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8
Fatty acid synthase inhibitor SureCN4564627 family 1 2
Nuclear receptor ROR-gamma and 4'-phosphopantetheinyl transfer... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 3-(2,4... 2 0
3-methyl-2-(quinolin-2-ylmethyl)-2H-furan-5-one NP 4-methyl-5-... 2 1
2-[2-(4-hydroxyphenyl)ethyl]-6-methylpyridin-1-ium-3-ol NP 2-(... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297484 DNC013352 Investigative Drug 3-hydroxy-5-(2-methylquinolin-7-yl)benzonitrile
CFAMM00297482 DNC013364 Investigative Drug 3-(2-methylquinolin-7-yl)phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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